It is traditionally believed that monastery Staro Hopovo was built by Despot Djuradj Branković by the end of the 15th and beginning of the 16th century, although the historical records mention it for the first time in 1546. The monastery church is dedicated to Saint Pantaleimon (or Pantaleon). A new church was built in 1752 on the foundations of an older one.
The church iconostasis dating back to the end of the 18th century was made in Rococo style and covered with gold. The throne icons were painted by Janko Halkozović. The monastery was damaged during the World War II and only some icons were preserved. An intensive renovation of the monastery has recently been in progress.